Signs of Low Estrogen in Women and How It Affects Health
At Triad Internal Medicine, Keung Lee, MD, PhD, MHA, helps women recognize and manage the subtle yet significant signs of low estrogen. Symptoms such as fatigue, mood swings, hot flashes, and irregular menstrual cycles can indicate a hormonal imbalance affecting bone, heart, and reproductive health. Dr. Lee provides personalized evaluations and care plans to restore balance, enhance energy, and support overall well-being for women at every stage of life. For more information, please contact us or book an appointment online. We are conveniently located at Dublin Square and Mack Road in Asheboro, NC.


Table of Contents:
What are the most common signs of low estrogen in women?
How does low estrogen affect a woman’s mood and emotions?
Can low estrogen cause hot flashes or night sweats?
Does low estrogen contribute to fatigue or low energy levels?
Recognizing the Health Effects of Low Estrogen in Women with Keung Lee, MD, PhD, MHA
We understand that low estrogen levels in women can lead to a variety of noticeable and often disruptive symptoms. One of the most common signs is irregular or missed periods, as estrogen is essential for regulating the menstrual cycle. Many women also experience hot flashes and night sweats, which are sudden feelings of warmth often accompanied by sweating and flushing. Vaginal dryness is another frequent symptom, potentially causing discomfort during intercourse and increasing the risk of urinary tract infections.
In addition, mood changes—such as increased irritability, anxiety, or depression—may also be linked to low estrogen. Other symptoms can include a decrease in libido, fatigue, and trouble sleeping. Over time, persistently low estrogen can lead to thinning bones, making women more susceptible to osteoporosis and fractures.
Our experienced healthcare providers are dedicated to helping women navigate these changes. If you are experiencing any of these symptoms, we encourage you to schedule an appointment for a thorough evaluation. Our team will work with you to determine the underlying cause and develop a personalized treatment plan to help you feel your best.
At Triad Internal Medicine, we understand that hormonal changes—especially low estrogen levels—can significantly influence a woman’s mood and emotional health. Estrogen is a vital hormone that not only regulates the reproductive system but also plays a key role in brain chemistry. It affects neurotransmitters like serotonin and dopamine, which are essential for mood stability, emotional balance, and overall feelings of well-being.
When estrogen levels decrease, whether due to natural life transitions such as perimenopause and menopause or certain medical conditions, many women experience noticeable changes in mood. Common symptoms include mood swings, increased irritability, persistent sadness or depression, anxiety, and trouble concentrating. These hormonal shifts can also disrupt sleep, which may further impact your mood and energy levels.
We recognize that every woman’s experience is unique. Our skilled providers are dedicated to identifying the root causes of your symptoms and offering personalized care. We can help determine if your emotional changes are related to low estrogen and discuss a variety of treatment options, such as lifestyle modifications, counseling, or hormone therapy, tailored to your individual needs.
We often see patients experiencing hot flashes and night sweats, especially women approaching or going through menopause. These symptoms are frequently caused by low estrogen levels, which commonly occur during perimenopause and menopause as the ovaries naturally reduce estrogen production.
Estrogen is essential for regulating the body’s temperature control system. When estrogen levels drop, the brain’s hypothalamus can become more sensitive to even minor changes in body temperature, leading to sudden feelings of warmth (hot flashes) and excessive sweating at night (night sweats).
While there are other potential causes for these symptoms, hormonal changes due to declining estrogen are among the most common reasons in women during midlife. If you are experiencing frequent hot flashes or night sweats, we encourage you to schedule an appointment. Our experienced healthcare providers can evaluate your symptoms, discuss potential hormonal changes, and work with you to find effective solutions for relief and improved quality of life.
We often see patients—especially women—who are concerned about persistent fatigue or low energy. One common but sometimes overlooked cause of these symptoms is low estrogen levels. This is particularly relevant for women going through menopause, perimenopause, or those experiencing conditions such as premature ovarian insufficiency.
Estrogen is a vital hormone that influences many aspects of your health, including your central nervous system, metabolism, and sleep cycles. When estrogen levels decline, as they often do during midlife and beyond, you may notice increased tiredness, difficulty concentrating, and a general sense of low vitality.
Estrogen also plays a key role in regulating neurotransmitters like serotonin and dopamine, which are crucial for mood and alertness. A drop in estrogen can disrupt these brain chemicals, leading to symptoms such as mood swings, irritability, and fatigue. Additionally, low estrogen levels may contribute to sleep disturbances, such as night sweats and hot flashes, further interfering with restful sleep and leaving you feeling exhausted during the day.
We recognize that estrogen also helps maintain healthy muscle and bone mass. Its decline can make physical activity feel more taxing and impact your overall energy levels. Changes in estrogen may even alter your metabolism, sometimes resulting in a sluggish feeling.
Low estrogen can affect more than just reproductive health—it can influence bone strength, metabolism, and cardiovascular function. At Triad Internal Medicine, Dr Lee helps women understand these broader health implications. Through careful testing and holistic evaluation, she ensures each patient receives guidance tailored to their individual needs.
If you are experiencing ongoing fatigue and think it may be related to hormonal changes, our experienced providers at Triad Internal Medicine are here to help. For more information, please contact us or book an appointment online. We are conveniently located at Dublin Square and Mack Road in Asheboro, NC. We serve patients from Asheboro NC, Redding Hills NC, Greensboro NC, Randleman NC, Sophia NC, Grays Chapel NC, and surrounding areas.
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